Nanostructured Calcium Phosphates: Preparation and Their Application in Biomedicine
نویسندگان
چکیده
Due to the similar chemical properties to the inorganic component in calcified tissues, synthetic calcium phosphate has been considered as ideal biomaterials with excellent biocompatibility. Nanostructured calcium phosphate materials play an important role in the formation of hard tissues in nature. It is reported that calcium phosphates materials in nano-size can mimic the dimensions of constituent components of calcified tissues. Recently, the synthesis and application of nanostructured calcium phosphate materials have become a very hot field. Lots of methods have been reported to prepare nanostructured calcium phosphate, and various morphologies including nanoparticles, plate-like nanocrystals, nano-needles, whiskers/fibres/ wires, mesoporous, nanotubes, nano-blades, and powders with three-dimensional (3-D) structures have been obtained. More studies of nanostructured calcium phosphates are expected in biomedical area, such as tissue engineering scaffolds, drug/gene delivery systems and multifunctional systems. In this article, the synthesis and application of nanostructured calcium phosphates are reviewed and discussed.
منابع مشابه
Investigation of the effective factors on manufacturing calcium phosphates prototypes using 3D printing
Calcium phosphate ceramics has been widely used in the present due to their chemical similarity to bone and good biocompatibility in the physiological environmental and a compatibility with synthetic and natural polymers Recent advancements in additive manufacturing have enabled the fabrication of 3D prototypes with controlled architecture resembling the natural bone. Binder jetting is a versat...
متن کاملMechanical Properties of Biomaterials Based on Calcium Phosphates and Bioinert Oxides for Applications in Biomedicine
متن کامل
Microwave-Assisted Hydrothermal Rapid Synthesis of Calcium Phosphates: Structural Control and Application in Protein Adsorption
Synthetic calcium phosphate (CaP)-based materials have attracted much attention in the biomedical field. In this study, we have investigated the effect of pH values on CaP nanostructures prepared using a microwave-assisted hydrothermal method. The hierarchical nanosheet-assembled hydroxyapatite (HAP) nanostructure was prepared under weak acidic conditions (pH 5), while the HAP nanorod was prepa...
متن کاملIon-Doped Silicate Bioceramic Coating of Ti-Based Implant
Titanium and its alloy are known as important load-bearing biomaterials. The major drawbacks of these metals are fibrous formation and low corrosion rate after implantation. The surface modification of biomedical implants through various methods such as plasma spray improves their osseointegration and clinical lifetime. Different materials have been already used as coatings on biomedical implan...
متن کاملPreparation and Properties of Nanoparticles of Calcium Phosphates With Various Ca/P Ratios
This study aimed at preparing and studying the properties of nanoparticles of calcium phosphate (nCaP) with Ca/P ratios ranging from 1.0 to 1.67 using a spray-drying technique. Micro-structural analyses suggested that the nCaPs with Ca/P ratios of 1.67 to 1.33 were nano-sized amorphous calcium phosphate (ACP) containing varying amounts of acid phosphate and carbonate. The nCaP with Ca/P ratio o...
متن کامل